Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.
Identifieur interne : 000351 ( Main/Exploration ); précédent : 000350; suivant : 000352Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.
Auteurs : Patricia R. Cury [Brésil] ; Franco Arsati ; Marina Helena Cury Gallottini De Magalhães ; Vera C. De Araújo ; Ney S. De Araújo ; José Alexandre BarbutoSource :
- Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [ 0275-1879 ]
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Antigènes CD (analyse), Antigènes CD1 (analyse), Antigènes de différenciation des myélomonocytes (analyse), Attache épithéliale (anatomopathologie), Attache épithéliale (immunologie), Cellules de Langerhans (anatomopathologie), Cellules de Langerhans (immunologie), Cellules dendritiques (anatomopathologie), Cellules dendritiques (immunologie), Cellules présentatrices d'antigène (anatomopathologie), Cellules présentatrices d'antigène (immunologie), Exsudat gingival (immunologie), Facteur XIIIa (analyse), Femelle (MeSH), Humains (MeSH), Hypertrophie gingivale (immunologie), Hypertrophie gingivale (induit chimiquement), Immunosuppresseurs (effets indésirables), Macrophages (anatomopathologie), Macrophages (immunologie), Mâle (MeSH), Parodonte (anatomopathologie), Parodonte (immunologie), Poche parodontale (anatomopathologie), Poche parodontale (immunologie), Techniques immunoenzymatiques (MeSH), Épithélium (anatomopathologie), Épithélium (immunologie).
- MESH :
- analyse : Antigènes CD, Antigènes CD1, Antigènes de différenciation des myélomonocytes, Facteur XIIIa.
- anatomopathologie : Attache épithéliale, Cellules de Langerhans, Cellules dendritiques, Cellules présentatrices d'antigène, Macrophages, Parodonte, Poche parodontale, Épithélium.
- effets indésirables : Immunosuppresseurs.
- immunologie : Attache épithéliale, Cellules de Langerhans, Cellules dendritiques, Cellules présentatrices d'antigène, Exsudat gingival, Hypertrophie gingivale, Macrophages, Parodonte, Poche parodontale, Épithélium.
- induit chimiquement : Hypertrophie gingivale.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Techniques immunoenzymatiques.
English descriptors
- KwdEn :
- Adult (MeSH), Antigen-Presenting Cells (immunology), Antigen-Presenting Cells (pathology), Antigens, CD (analysis), Antigens, CD1 (analysis), Antigens, Differentiation, Myelomonocytic (analysis), Dendritic Cells (immunology), Dendritic Cells (pathology), Epithelial Attachment (immunology), Epithelial Attachment (pathology), Epithelium (immunology), Epithelium (pathology), Factor XIIIa (analysis), Female (MeSH), Gingival Crevicular Fluid (immunology), Gingival Hypertrophy (chemically induced), Gingival Hypertrophy (immunology), Humans (MeSH), Immunoenzyme Techniques (MeSH), Immunosuppressive Agents (adverse effects), Langerhans Cells (immunology), Langerhans Cells (pathology), Macrophages (immunology), Macrophages (pathology), Male (MeSH), Middle Aged (MeSH), Periodontal Pocket (immunology), Periodontal Pocket (pathology), Periodontium (immunology), Periodontium (pathology).
- MESH :
- chemical , adverse effects : Immunosuppressive Agents.
- chemical , analysis : Antigens, CD, Antigens, CD1, Antigens, Differentiation, Myelomonocytic, Factor XIIIa.
- chemically induced : Gingival Hypertrophy.
- immunology : Antigen-Presenting Cells, Dendritic Cells, Epithelial Attachment, Epithelium, Gingival Crevicular Fluid, Gingival Hypertrophy, Langerhans Cells, Macrophages, Periodontal Pocket, Periodontium.
- pathology : Antigen-Presenting Cells, Dendritic Cells, Epithelial Attachment, Epithelium, Langerhans Cells, Macrophages, Periodontal Pocket, Periodontium.
- Adult, Female, Humans, Immunoenzyme Techniques, Male, Middle Aged.
Abstract
An immunoperoxidase technique was used to compare the number of CD1a+ and factor XIIIa+ dendritic cells (DCs), and CD68+ Macrophages (M) in 30 gingival samples from subjects with clinically healthy periodontitium (HP) and 10 samples from subjects with drug-induced gingival enlargement (DIGE). Fewer CD1a+ and factor XIIIa+ DCs were found in areas with inflammatory infiltration (II) of the lamina propria (LP) in the group with immunosuppressed DIGE (IDIGE) compared to the group with HP. In the sulcular and junctional/pocket epithelia, the number of CD1a+ DCs was decreased in the group with IDIGE (p<0.05). There was a tendency toward a reduced number of CD1a+ DCs and CD68+ M in areas without inflammatory infiltrate of the LP in the group with IDIGE. The alterations in the number of antigen-presenting cells (APCs) may be the reason for the decreased periodontal inflammation and breakdown clinically observed in subjects who are immunosuppressed.
DOI: 10.1111/j.1754-4505.2008.00067.x
PubMed: 19284507
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.</title><author><name sortKey="Cury, Patricia R" sort="Cury, Patricia R" uniqKey="Cury P" first="Patricia R" last="Cury">Patricia R. Cury</name><affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology and Immunology, São Leopoldo Mandic Dental Research Center, Campinas, São Paulo, Brazil. patcury@yahoo.com</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Microbiology and Immunology, São Leopoldo Mandic Dental Research Center, Campinas, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Arsati, Franco" sort="Arsati, Franco" uniqKey="Arsati F" first="Franco" last="Arsati">Franco Arsati</name></author><author><name sortKey="De Magalhaes, Marina Helena Cury Gallottini" sort="De Magalhaes, Marina Helena Cury Gallottini" uniqKey="De Magalhaes M" first="Marina Helena Cury Gallottini" last="De Magalhães">Marina Helena Cury Gallottini De Magalhães</name></author><author><name sortKey="De Araujo, Vera C" sort="De Araujo, Vera C" uniqKey="De Araujo V" first="Vera C" last="De Araújo">Vera C. De Araújo</name></author><author><name sortKey="De Araujo, Ney S" sort="De Araujo, Ney S" uniqKey="De Araujo N" first="Ney S" last="De Araújo">Ney S. De Araújo</name></author><author><name sortKey="Barbuto, Jose Alexandre" sort="Barbuto, Jose Alexandre" uniqKey="Barbuto J" first="José Alexandre" last="Barbuto">José Alexandre Barbuto</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009 Mar-Apr</date><idno type="RBID">pubmed:19284507</idno><idno type="pmid">19284507</idno><idno type="doi">10.1111/j.1754-4505.2008.00067.x</idno><idno type="wicri:Area/Main/Corpus">000367</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000367</idno><idno type="wicri:Area/Main/Curation">000367</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000367</idno><idno type="wicri:Area/Main/Exploration">000367</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.</title><author><name sortKey="Cury, Patricia R" sort="Cury, Patricia R" uniqKey="Cury P" first="Patricia R" last="Cury">Patricia R. Cury</name><affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology and Immunology, São Leopoldo Mandic Dental Research Center, Campinas, São Paulo, Brazil. patcury@yahoo.com</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Department of Microbiology and Immunology, São Leopoldo Mandic Dental Research Center, Campinas, São Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Arsati, Franco" sort="Arsati, Franco" uniqKey="Arsati F" first="Franco" last="Arsati">Franco Arsati</name></author><author><name sortKey="De Magalhaes, Marina Helena Cury Gallottini" sort="De Magalhaes, Marina Helena Cury Gallottini" uniqKey="De Magalhaes M" first="Marina Helena Cury Gallottini" last="De Magalhães">Marina Helena Cury Gallottini De Magalhães</name></author><author><name sortKey="De Araujo, Vera C" sort="De Araujo, Vera C" uniqKey="De Araujo V" first="Vera C" last="De Araújo">Vera C. De Araújo</name></author><author><name sortKey="De Araujo, Ney S" sort="De Araujo, Ney S" uniqKey="De Araujo N" first="Ney S" last="De Araújo">Ney S. De Araújo</name></author><author><name sortKey="Barbuto, Jose Alexandre" sort="Barbuto, Jose Alexandre" uniqKey="Barbuto J" first="José Alexandre" last="Barbuto">José Alexandre Barbuto</name></author></analytic><series><title level="j">Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry</title><idno type="ISSN">0275-1879</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Antigen-Presenting Cells (immunology)</term><term>Antigen-Presenting Cells (pathology)</term><term>Antigens, CD (analysis)</term><term>Antigens, CD1 (analysis)</term><term>Antigens, Differentiation, Myelomonocytic (analysis)</term><term>Dendritic Cells (immunology)</term><term>Dendritic Cells (pathology)</term><term>Epithelial Attachment (immunology)</term><term>Epithelial Attachment (pathology)</term><term>Epithelium (immunology)</term><term>Epithelium (pathology)</term><term>Factor XIIIa (analysis)</term><term>Female (MeSH)</term><term>Gingival Crevicular Fluid (immunology)</term><term>Gingival Hypertrophy (chemically induced)</term><term>Gingival Hypertrophy (immunology)</term><term>Humans (MeSH)</term><term>Immunoenzyme Techniques (MeSH)</term><term>Immunosuppressive Agents (adverse effects)</term><term>Langerhans Cells (immunology)</term><term>Langerhans Cells (pathology)</term><term>Macrophages (immunology)</term><term>Macrophages (pathology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Periodontal Pocket (immunology)</term><term>Periodontal Pocket (pathology)</term><term>Periodontium (immunology)</term><term>Periodontium (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Antigènes CD (analyse)</term><term>Antigènes CD1 (analyse)</term><term>Antigènes de différenciation des myélomonocytes (analyse)</term><term>Attache épithéliale (anatomopathologie)</term><term>Attache épithéliale (immunologie)</term><term>Cellules de Langerhans (anatomopathologie)</term><term>Cellules de Langerhans (immunologie)</term><term>Cellules dendritiques (anatomopathologie)</term><term>Cellules dendritiques (immunologie)</term><term>Cellules présentatrices d'antigène (anatomopathologie)</term><term>Cellules présentatrices d'antigène (immunologie)</term><term>Exsudat gingival (immunologie)</term><term>Facteur XIIIa (analyse)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Hypertrophie gingivale (immunologie)</term><term>Hypertrophie gingivale (induit chimiquement)</term><term>Immunosuppresseurs (effets indésirables)</term><term>Macrophages (anatomopathologie)</term><term>Macrophages (immunologie)</term><term>Mâle (MeSH)</term><term>Parodonte (anatomopathologie)</term><term>Parodonte (immunologie)</term><term>Poche parodontale (anatomopathologie)</term><term>Poche parodontale (immunologie)</term><term>Techniques immunoenzymatiques (MeSH)</term><term>Épithélium (anatomopathologie)</term><term>Épithélium (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Immunosuppressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antigens, CD</term><term>Antigens, CD1</term><term>Antigens, Differentiation, Myelomonocytic</term><term>Factor XIIIa</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Antigènes CD</term><term>Antigènes CD1</term><term>Antigènes de différenciation des myélomonocytes</term><term>Facteur XIIIa</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Attache épithéliale</term><term>Cellules de Langerhans</term><term>Cellules dendritiques</term><term>Cellules présentatrices d'antigène</term><term>Macrophages</term><term>Parodonte</term><term>Poche parodontale</term><term>Épithélium</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Gingival Hypertrophy</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Immunosuppresseurs</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Attache épithéliale</term><term>Cellules de Langerhans</term><term>Cellules dendritiques</term><term>Cellules présentatrices d'antigène</term><term>Exsudat gingival</term><term>Hypertrophie gingivale</term><term>Macrophages</term><term>Parodonte</term><term>Poche parodontale</term><term>Épithélium</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Antigen-Presenting Cells</term><term>Dendritic Cells</term><term>Epithelial Attachment</term><term>Epithelium</term><term>Gingival Crevicular Fluid</term><term>Gingival Hypertrophy</term><term>Langerhans Cells</term><term>Macrophages</term><term>Periodontal Pocket</term><term>Periodontium</term></keywords><keywords scheme="MESH" qualifier="induit chimiquement" xml:lang="fr"><term>Hypertrophie gingivale</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Antigen-Presenting Cells</term><term>Dendritic Cells</term><term>Epithelial Attachment</term><term>Epithelium</term><term>Langerhans Cells</term><term>Macrophages</term><term>Periodontal Pocket</term><term>Periodontium</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Humans</term><term>Immunoenzyme Techniques</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Techniques immunoenzymatiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">An immunoperoxidase technique was used to compare the number of CD1a+ and factor XIIIa+ dendritic cells (DCs), and CD68+ Macrophages (M) in 30 gingival samples from subjects with clinically healthy periodontitium (HP) and 10 samples from subjects with drug-induced gingival enlargement (DIGE). Fewer CD1a+ and factor XIIIa+ DCs were found in areas with inflammatory infiltration (II) of the lamina propria (LP) in the group with immunosuppressed DIGE (IDIGE) compared to the group with HP. In the sulcular and junctional/pocket epithelia, the number of CD1a+ DCs was decreased in the group with IDIGE (p<0.05). There was a tendency toward a reduced number of CD1a+ DCs and CD68+ M in areas without inflammatory infiltrate of the LP in the group with IDIGE. The alterations in the number of antigen-presenting cells (APCs) may be the reason for the decreased periodontal inflammation and breakdown clinically observed in subjects who are immunosuppressed.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19284507</PMID><DateCompleted><Year>2009</Year><Month>08</Month><Day>04</Day></DateCompleted><DateRevised><Year>2009</Year><Month>03</Month><Day>16</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0275-1879</ISSN><JournalIssue CitedMedium="Print"><Volume>29</Volume><Issue>2</Issue><PubDate><MedlineDate>2009 Mar-Apr</MedlineDate></PubDate></JournalIssue><Title>Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry</Title><ISOAbbreviation>Spec Care Dentist</ISOAbbreviation></Journal><ArticleTitle>Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.</ArticleTitle><Pagination><MedlinePgn>80-4</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1754-4505.2008.00067.x</ELocationID><Abstract><AbstractText>An immunoperoxidase technique was used to compare the number of CD1a+ and factor XIIIa+ dendritic cells (DCs), and CD68+ Macrophages (M) in 30 gingival samples from subjects with clinically healthy periodontitium (HP) and 10 samples from subjects with drug-induced gingival enlargement (DIGE). Fewer CD1a+ and factor XIIIa+ DCs were found in areas with inflammatory infiltration (II) of the lamina propria (LP) in the group with immunosuppressed DIGE (IDIGE) compared to the group with HP. In the sulcular and junctional/pocket epithelia, the number of CD1a+ DCs was decreased in the group with IDIGE (p<0.05). There was a tendency toward a reduced number of CD1a+ DCs and CD68+ M in areas without inflammatory infiltrate of the LP in the group with IDIGE. The alterations in the number of antigen-presenting cells (APCs) may be the reason for the decreased periodontal inflammation and breakdown clinically observed in subjects who are immunosuppressed.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cury</LastName><ForeName>Patricia R</ForeName><Initials>PR</Initials><AffiliationInfo><Affiliation>Department of Microbiology and Immunology, São Leopoldo Mandic Dental Research Center, Campinas, São Paulo, Brazil. patcury@yahoo.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arsati</LastName><ForeName>Franco</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>de Magalhães</LastName><ForeName>Marina Helena Cury Gallottini</ForeName><Initials>MH</Initials></Author><Author ValidYN="Y"><LastName>de Araújo</LastName><ForeName>Vera C</ForeName><Initials>VC</Initials></Author><Author ValidYN="Y"><LastName>de Araújo</LastName><ForeName>Ney S</ForeName><Initials>NS</Initials></Author><Author ValidYN="Y"><LastName>Barbuto</LastName><ForeName>José Alexandre</ForeName><Initials>JA</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Spec Care Dentist</MedlineTA><NlmUniqueID>8103755</NlmUniqueID><ISSNLinking>0275-1879</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015703">Antigens, CD</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018949">Antigens, CD1</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015214">Antigens, Differentiation, Myelomonocytic</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C419393">CD1a antigen</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C067980">CD68 antigen, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007166">Immunosuppressive Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.3.2.13</RegistryNumber><NameOfSubstance UI="D026122">Factor XIIIa</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000938" MajorTopicYN="N">Antigen-Presenting Cells</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015703" MajorTopicYN="N">Antigens, CD</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018949" MajorTopicYN="N">Antigens, CD1</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015214" MajorTopicYN="N">Antigens, Differentiation, Myelomonocytic</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003713" MajorTopicYN="N">Dendritic Cells</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004846" MajorTopicYN="N">Epithelial Attachment</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004848" MajorTopicYN="N">Epithelium</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D026122" MajorTopicYN="N">Factor XIIIa</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005883" MajorTopicYN="N">Gingival Crevicular Fluid</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005886" MajorTopicYN="N">Gingival Hypertrophy</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007124" MajorTopicYN="N">Immunoenzyme Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007166" MajorTopicYN="N">Immunosuppressive Agents</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007801" MajorTopicYN="N">Langerhans Cells</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008264" MajorTopicYN="N">Macrophages</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010514" MajorTopicYN="N">Periodontal Pocket</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010519" MajorTopicYN="N">Periodontium</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>3</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>3</Month><Day>17</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2009</Year><Month>8</Month><Day>6</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19284507</ArticleId><ArticleId IdType="pii">SCD067</ArticleId><ArticleId IdType="doi">10.1111/j.1754-4505.2008.00067.x</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Brésil</li></country><region><li>État de São Paulo</li></region><settlement><li>São Paulo</li></settlement></list><tree><noCountry><name sortKey="Arsati, Franco" sort="Arsati, Franco" uniqKey="Arsati F" first="Franco" last="Arsati">Franco Arsati</name><name sortKey="Barbuto, Jose Alexandre" sort="Barbuto, Jose Alexandre" uniqKey="Barbuto J" first="José Alexandre" last="Barbuto">José Alexandre Barbuto</name><name sortKey="De Araujo, Ney S" sort="De Araujo, Ney S" uniqKey="De Araujo N" first="Ney S" last="De Araújo">Ney S. De Araújo</name><name sortKey="De Araujo, Vera C" sort="De Araujo, Vera C" uniqKey="De Araujo V" first="Vera C" last="De Araújo">Vera C. De Araújo</name><name sortKey="De Magalhaes, Marina Helena Cury Gallottini" sort="De Magalhaes, Marina Helena Cury Gallottini" uniqKey="De Magalhaes M" first="Marina Helena Cury Gallottini" last="De Magalhães">Marina Helena Cury Gallottini De Magalhães</name></noCountry><country name="Brésil"><region name="État de São Paulo"><name sortKey="Cury, Patricia R" sort="Cury, Patricia R" uniqKey="Cury P" first="Patricia R" last="Cury">Patricia R. Cury</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SuicidDentistV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000351 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000351 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SuicidDentistV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:19284507
|texte= Antigen-presenting cells in human immunosuppressive drug-induced gingival enlargement.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:19284507" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SuicidDentistV1
| This area was generated with Dilib version V0.6.39. |  |